Lactate & Enzymes Essay Example | Topics and Well Written Essays - 1750 words

Lactate & Enzymes - Essay Example If pyruvate does not break down, it usually turns into lactate. When pyruvate is produced, the muscle cell will try to use it for aerobic energy. However, if the cell does not have the capacity to use all the pyruvate produced, it will be changed chemically to lactate. Some cells have a large capacity to use pyruvate for aerobic energy while others have very little. With training, many cells can adapt to use more pyruvate and, thus, produce less lactate. Lactate is present in our system at rest and as we go about our every day activities, although at low levels. However, as exercise or work activity increases in intensity, large amounts of pyruvate are produced very quickly. Because pyruvate can be produced quickly, not all of it may be used for aerobic energy. The surplus pyruvate will turn into lactate. This is why lactate is such a significant marker for training. When it is produced, it is a sign that aerobic energy is limited during the activity. There is a different reason why more lactate is produced as exercise intensity increases. As exercise increases, extra muscle fibers will be recruited. These fibers are used infrequently at rest or in light activity. Fast twitch fibers are not very good at turning pyruvate into aerobic energy. Hence, a lot of this pyruvate turns into lactate. Lactate is a major metabolic intermediate. Its fate depends on the conditions of the cell. In aerobic oxidation of glucose, glucose is converted to pyruvate, which is then converted to acetylSCoA (or AcetylCoA), a high-energy thioester. Under anaerobic conditions, pyruvate is reduced to lactate to regenerate the NAD + needed in Step 6 of glycolysis to keep glycolysis pathway going. 3. Which enzyme is responsible for lactate production Write out the equation for this reaction. Lactate Dehydrogenase (LDH) is an enzyme responsible for lactate production, which is present in varieties or organisms including plants and animals. This will catalyse the inter-conversion of pyruvate and lactate with concomitant inter-conversion of NADH and NAD+. As it can also catalyze the oxidation of hydroxybutyrate, occasionally called Hydroxybutyrate Dehydrogenase (HBD). Or D(-)Lactate + -NAD + Hydrazine LDH> Pyruvate Hydrazone + -NADH Abbreviations used: -NAD = -Nicotinamide Adenine Dinucleotide, Oxidized Form -NADH = -Nicotinamide Adenine Dinucleotide, Reduced Form LDH = D-Lactic Dehydrogenase 4. The student decided to use this enzyme to measure blood lactate levels. He reasoned that if he could produce reaction conditions that allowed the enzyme to metabolise all the lactate present, he would be able to calculate the lactate content of his sample by reading the change in absorbance at 340nm. Explain the reasoning behind this idea. LDH catalyzes the reduction of pyruvate to L-lactate with concomitant oxidation of NADH2 to NAD. Since the oxidation of NADH2 is directly proportional to the reduction of pyruvate in equimolar amounts, the LDH activity can be calculated from the rate of decrease in absorbance at 340 nm (334 nm or 365 nm). 5. In order to obtain suitable conditions for an assay to measure plasma lactate levels, the student chose a buffer containing 1.5% (w/v) hydrazine. Hydrazine reacts covalently with pyruvate to form a hydrazone: CH3 CH3 | | C=O + NH2.NH2 C=N.NH2+H20 |

Novel Essay Example | Topics and Well Written Essays - 1500 words

Novel - Essay Example The story of their destruction started from their elopement, which was decided because Manon was not accepted by Des Grieux’s father. On the other hand, â€Å"The Sorrows of young Werther† indicate class as a burden for Werther, who is unable to endure the difficulties of class. Werther develops a love for simplicity for peasants and likes their class. He is unable to endure the snobbishness of his own and upper classes. As far as â€Å"Silas Marner† is concerned, class is depicted by means of physical locations. The home of Silas Marner is the lowliest place while the home of Godfrey Cass is the highest place of the locality but in spite of all the riches, the wife of Godfrey is jealous of Silas and Eppie because she is unable to bear a child. All the three novels take class with a different perspective but all their perspectives are persuasive and influential in different places. The theme of class id dealt differently in each writing. Class is a reality that i s considered differently by all the three writers. The novel, Manon Lescaut, takes the theme of love and combines it to the theme of class. The example of class based society can be taken from the incident when Des Grieux has to make a decision to elope in order to marry his beloved, who belongs to a lower class family. Manon Lescaut is a story of a lover who leaves his noble and landed family because of his beloved. The protagonist of the novel le Chevalier Des Grieux belongs to a noble and rich family and his father keeps higher hopes with his son but with the passage of time, Des Grieux’s father is disappointed as Des Grieux elopes with her beloved, Manon Lescaut. At various occasions in the novel, there are indications of Manon Lescaut’s intention of leaving Des Grieux because of his lack of money (Arnold 1981). He belonged to a noble class but with the passage of time, he is unable to maintain his social status because he has left his hereditary wealth for his beloved, who was

A Happy University Essay Example for Free

A Happy University Essay A happy university is enjoyable and interesting place to study. Students feel that they belong to a community and are offered supports from the Student Assistance Center of the university. The university is well-designed and there are many good facilities. A happy campus also has many interesting and exciting places for recreation. Students in happy campus have good behavior. Although they come from different background, they are able to respect each other and share ideas. They also help other students to overcome issues about study or life. Especially freshmen who have just started their term at the university, they are taught life skills and get assistances from the Student Assistance Center to be familiar with new life and environment. In addition there are many opportunities for students to take part in community or social events, and do part-time jobs to earn money to buy books or equipment for study. Good facilities is one of the factors that cannot be missing in a happy campus. There are areas for study and a library with internet connection and an enormous amount of books that are always revised. It also has large lecture rooms, laboratories, a medical center. These laboratories are designed specifically base on different specialties. In addition, there is a big smart parking basement that helps students to easily and quickly keep or take their bikes or cars. Moreover, the university has high standard of teaching with modern resources and equipment. Students is easy to move around the campus because the footpaths and connecting bridges are well-organized. After spending long period of time for study or research, students cannot avoid suffering from fatigue or mental illnesses such as tiredness, depression, insomnia. Therefore they need to refresh their soul or stay mentally healthy. So many places for recreation are built up because of that purpose. There are many green fields such as parks, gardens, small hills on the bank of rivers and sporting fields such as football grounds, swimming pools, basketball courts, golf courses, F1 circuits. Students can spend their free time in these areas or in fitness center, spas or yoga. Besides sports or exercises, they can also take part in extracurricular activities depend on their hobbies such as singing, dancing, drawing or writing for the university newspaper. On weekends, they can gather at a nightclub that has performances of famous DJs and singers such as Tiesto, David Guetta, Justin Timberlake, Rihanna. However, the nightclub is only celebrated on special event. Additionally,  students can join groups which organize debates, meetings and holiday trips. Finally, in memory of people who have studied at a happy university that are unforgettable days and experiences. They are also proud of being students of a happy university.

Religion Is The Opium Of The People Philosophy Essay

Religion Is The Opium Of The People Philosophy Essay Religion is the opium of the people Karl Marx, Critique of Hegels Philosophy of Right, 1844 The construct of two uniquely different terms being used together often raises the eyes of persons who focus on strategies to influence the thinking and actions of many persons. In this case, religion represents those persons around the globe who hold strongly held beliefs. Opium, conversely, often represents an addictive substance that shifts the ability of individuals to maintain control of their own faculties, abilities, or behaviors. Each term provides numerous images in the minds of people who value either religion or the use of substances. In this case, however, the terms are used in a statement of emphasis that demands that one see the critical direction that Karl Marx was approaching in 1844. According to Oxford Dictionaries (2009), Religion is the belief in and worship of a superhuman controlling power, especially a personal God or gods. Opium is a reddish -brown heavy-scented addictive drug prepared from the juice of the opium poppy, used illicitly as a narcotic and occasionally in medicine as an analgesic. The opium of the people is a thought and action-reaction regarded as inducing a false and unrealistic sense of contentment among people. In this case, it is Religion, according to Marx. History reports that the majority of people believe that Marx criticizes religion as being a relief for the masses, in the way that it creates an illusory fantasy to the poor, assuring them that even if they are living in misery in this life, they will find true happiness in the afterlife, thus only masking the problem and not solving it. However, based on the sudden change in the 19th century (period in which Marx lived) of how opium is perceived, the quote can be assessed in two way s; positively and negatively. This makes it interesting for us to analyze it since history plays a big part on how it should be understood. Since prehistoric times, opium has been used worldwide. From Egypt to China, it was highly regarded and used for many things, such as to relieve pain, to bring courage and strength to soldiers, to reach a feeling of ecstasy or to get in touch with the divine. These practices continued and spread, until the 19th century, when its negative effects were being detected. At this point, opium was found to be addictive, sometimes lethal and had started to be regulated. The impact and harm that was done through the use of opium caused societies to consider changing the perspective held on the use of the drug. Eventually, the use of opium became illegal because its damage was significant to the members of every society where it was used. Parenthetically, it was and sometimes still is being used for medical experiments and pain-reduction, delusional practices to this day and remains the most efficient pain-killer. However, despite the illegalization of opium and its derivatives, it was and is still being used by a wide variety of people in all parts of the world, most commonly in the form of heroin, in order to achieve a feeling of pleasure and to escape from reality. In the 19th century, opium was responsible for two wars that took place between the United Kingdom and China. The Opium Wars occurred because China illegalized the drug though the United Kingdom continued to traffic it in China, through India. After having had an overview on the history of opium, we can now deduce the different possible meanings that Marx conveys in his quote. In a first perspective, Marx could imply that religion is the opium of the people in a positive manner. This being the case, Marx meant that opium provides comfort and relief. Since Marx was a big supporter of the proletarian movement, which in his time was working in horrible conditions and leading miserable lives in cities, Marx might have insinuated that religions purpose was to create illusory fantasies for the poor as opium did for drug abusers and addicts. Economic realities often prevented the poor and to a large extent, even the aristocrats, from finding true happiness in this life; so religion tells them that this is OK because through a belief in God, through accepting the power and authority of God; through dying and going to heaven, one will find true happiness in the next life. Additionally, religion might bring comfort to people in hard times, for example during times of war, when people would pray for God to protect them, or after the death of a loved one, thinking thi s person would go to heaven and be at peace. Another argument would be that religion and opium give courage to people. Christians and Muslims believe that God Allah is always with them, protecting them and loving them, which could boost their confidence and make them feel they can do anything with God on their side. Lastly, religion can give, for some, a purpose to life based on the principles and tenets of God suggesting that God has a plan for each human being. Moreover, it explains all that science is unable to explain, for example the creation of the Human race. Effectually, what is not scientific is created by faith often unchallengeable in the eyes of rational thought. To conclude, Marx could be stating by his quote that people are in distress and religion provides solace, just as people who are physically injured receive relief from opiate-based drugs. On the other hand, Marx could very well be criticizing religion. First of all, opiates do not fix a physical injury, they merely make you forget pain for a limited time; this is a good thing only if you work on solving the underlying roots of the pain. Equivalently, religion doesnt fix peoples pain, it simply conceals their reasons of suffering and causes them to look ahead to an illusory future when the pain will cease, instead of working on changing their present condition. In other words, Religion as opium creates an imaginary world that prevents people from being accountable for their own lives and their own futures since they believe their path is traced and controlled by a certain God. They are thus led to let things happen and not be responsible for the situation in which they are. Moreover, religion is used as a control mechanism that gives power and authority of some over the masses. The desire to create a collective unconscious that diminishes the power of man to an acquies cing to the power and authority of a higher power often unseen and unknown. Because of the unknown nature -there is a concern that the higher power is infinite; man is finite, and in that finite nature, man can never be in control of his own destiny. Thus, man must acquiesce to the power of the higher authority, and its emissary on earth the Church. However, the church is the work of man and is bound to be flawed. For example, regarding Christianity, Jesus advocated helping the poor, but the Christian church merged with the oppressive Roman state, taking part in the enslavement of people for centuries. In the Middle-Ages the Catholic Church preached about heaven, but acquired as much property and power as possible. Finally, religion, just like opium, is a cause of war. Opium was the cause of two wars between the United Kingdom and China in the 19th century. Similarly, religion was the cause of the crusades, a war between Christians and Muslims that lasted nearly two centuries. This could be one of the reasons why Marx associated the word opium with religion. The quote Religion is the opium of the people can apply to the two major religions: Christianity and Islam. Both religions believe in one God, and both believe in a final judgment, where a person is judged according to their actions on earth, and then sent to either Heaven, place of joy and bliss where they will be happy, either in Hell where they will spend an eternity of misery. On the other hand, other religions such as Hinduism and Buddhism believe in reincarnation of the spirit, which means the person might or might not be happy in his new life, and this excludes Marxs theory of religion being a comfort to the people.

Essay --

Suicide is a permanent solution to what is often a temporary problem. Suicide not only affects the individual but it also affects all the people that surround that one person who committed suicide. When a person decides he/she wants to die they commit this act. But, when a person attempts suicide and is unsuccessful this can lead to that individual to be in more pain to include: broken bones to brain damage. An unsuccessful, suicide attempt can cause the person to sink further into depression as well. There are many contributing factors when dealing with someone who wants to commit suicide but there are also a few myths that are associated with suicide as well. When people talk about committing suicide to another person this does not necessarily mean that they want to kill themselves, but it just might be that they are reaching out or crying for help. There are many different myths associated with suicide. Myths like: people who talk about suicide are just trying to get attention; f rom suicide occurring without warning; and suicidal people not wanting to die. To identify theses myths one must understand why someone would want to end their life. With over 38,000 suicides in 2010 The Center for Disease Control and Prevention claims that is an average of 105 each day. â€Å"There is one suicide for every 25 attempted suicides and suicide results in an estimated $34.6 billion in combined medical and work-loss costs†. (States News Service) People who want to commit suicide can attribute these thoughts to many factors. Factors like family history of suicide, attempted suicide and depression, alcohol and drug problems also contribute to the thoughts of suicide. Warning signs are identified in many different ways and they also change with age... ... Did he want to die? His mind was not yet matured as most teenagers minds are. He just wanted the feeling of loss to stop. That was his cry for help. Luckily, it was only for a short time. â€Å"According to the Mayo Clinic, information was released relating to debunking certain myths about suicide. â€Å"The majority of people contemplating suicide don't really want to die. They are seeking an end to intense mental and/or physical pain. Most have a treatable mental illness. Interventions can save lives.† (â€Å"States News Service†) Suicide is a very serious condition that affects the lives of not only the individual who commits suicide, but it affects all the people who are involved with that individual. When we can separate the facts from the myths about suicide, we could possibly prevent a suicide and save someone’s life. Everyone should know the facts, it can save a life.

Vying For A Title :: essays research papers

Vying for a Title   Ã‚  Ã‚  Ã‚  Ã‚  The contenders have been primped and manicured by their masters and are ready to be placed on display. The subjects with the wealthiest owners attend top-notch obedience schools where they are trained in the art of acting and appearing in a way uncharacteristic to their nature. They are rewarded with special treats when they work hard during training. The skills learned in these unique schools are not useful anywhere else, but in the competitions are judged and often given a champion prize. The contestants are paraded in, coached by their owners. Each standing tall with her head raised and nose up. Most are showing their teeth as if to be smiling or happy. Truthfully, they are showing the judges the straightness and whiteness of their teeth. Both the long-haired and short-haired have had chemicals applied to them to make certain every hair lays perfectly. The outward appearances of the participators are close to flawless. If any flaws are detected in the preparation they are quickly covered up. Trainers and owners see imperfections as point deductions. Those are deductions they can’t afford when a title and thousands of dollars are on the line. A woman moves from one contestant to the next testing them. To the last in the line of female competitors the question is asked, â€Å"If you could change the world, what would you change?† Too confidently the girl replied, â€Å"I would end world hunger and poverty.† When all she really aspires to do is win this contest and the next. This is what pageantry is about. Parents who subject their children to beauty pageants teach their children that winning these contests will bring them happiness. Is being deemed the best at being fake really anything to be happy about? Too many mommies and daddies believe so. Do the pageant parents have their own dreams about their daughters being Miss Americas? Do the participants really compete in beauty contests to better themselves or their futures? Do they have a driving force from behind the stage? Will these parents go to any extent to mold their daughters into something that might win a few of these superficial contests? â€Å"†¦Didn't the Ramseys think that putting JonBenet in all those beauty pageants, looking so seductive, was inappropriate. The child was 5. All the pictures we saw were of her looking 25 and slinking and winking.† (Schwartz) â€Å"Mrs. Ramsey said that was just the public's problem and if they thought a 5-year-old trying to look more sexy than Madonna was a bit twisted - well that just shows what twisted people we have in this country.

A pleasurable environment

AN ASSESSMENT OF THE IMPACT OF POLICY AND LAW IN THE MITIGATION OF ENVIRONMENTAL CRIME.An person ‘s character is determined by his life status, it is no secret that the environment an single finds himself has an tremendous influence on his character, which could be either positive or negative. Our vision of holding a enjoyable environment is being ruined by actions committed by either persons, corporate organic structures or concern administrations that disrupt the peace and hygiene of our environment, these actions are referred to as environmental offense. ( House of Commons Environmental Audit Committee 2005, p.8 ) . An Environmental offense is an environmental issue several writers and authors have made effort to specify from their ain point of position. An environmental offense as defined by the Staffordshire Moor lands District Council ( 2009 ) is an improper act which ruin the visual aspect of some portion of the environment, it could take to pollution of the environment, wellness and safety concerns and it can hold a negative consequence on the enjoyment of our territory. Situ and Emmons ( 2000, p.3 ) refers to environmental offense as an inadvertence that violates the jurisprudence and attracts condemnable test and countenance. This offense endangers the safety of persons both physically, wellness wise and environmentally. Clifford ( 1998, p.26 ) believes that an environmental offense is an knowing act committed to potentially do injury to the ecological and biological systems of the environment and besides for the intent of procuring concern or personal benefit, While the Sixth study of the Environmental Audit Committee states that environmental offense comprises all offenses either formed by statues or developed under the comm on jurisprudence that relates to the environment. Environmental Investigation Agency ( EIA ) ( 2009 ) goes farther to specify environmental offense as the interruption of international pacts designed to command trade in substances harmful to the environment or bound trade in rare species or improper Acts of the Apostless which cause direct injury to the environment straight. Stratford -on-Avon District Council ( 2009 ) defines environmental offense as a type of anti-social behavior that affects the value of life of the community and environment where the offense occurs and enhances the fright of offense. This is similar to the definition of environmental offense by Warwickshire Council ( 2009 ) as activities that are against the jurisprudence and are harmful to the quality of unrecorded and the environment. Environmental Crime may include the undermentioned and many more: Fly tipping Graffiti Littering Fly-posting Abandoned Vehicles Dog fouling Panpipes Vandalism Noise Pollution Extra Side Waste House holders Duty attention Wild life Crime Pollution Crime Improper waste disposal Oil spills Dumping into Oceans, Streams, Lakes or rivers Improper handling of pesticides or other toxic chemicals Burning Garbage Falsifying Lab informations pertaining to environmental ordinance Sourced from assorted writers: Daventory District Council ( 2009 ) , Interpol ( 2009 ) , LawyerShop ( 2008 ) , Straford – on- Avon District council ( 2009 ) , Working Borough Council ( 2008 ) . These are really of import environmental issues that affect our environments merchandise and place. Here one can place several inquiries: Can the most common of these offenses be defined? What chance exists for an environment in which these offenses occur? What has be done by the Law to if non wholly eliminate these offenses at least cut down their happening drastically? What can I make to assist cut down environmental offense in my environment? Violators of the environmental jurisprudence are normally charged with condemnable mulcts, gaol clip, test or other penalty ordered by the local governments. Although fixed punishment mulcts are used as bar to large companies from go againsting environmental Torahs and policy without the hazard of sedate pecuniary penalty, most large companies might happen that noncompliance is more expensive than obeisance to the jurisprudence, while jail clip may be the best manner to penalize persons who participate or commit environmental offense. ( Lawye r store 2008 ) . The Environmental Protection Agency is in charge of enforcement over environmental jurisprudence misdemeanor. ( Lawyer Shop 2008 ) . There are offenses that wild occur in our environment which have largely been considered by bulk as environmental offenses, offenses such as: Fly tipping: This could be referred to as illegal dumping of family waste such as old house clasp contraptions ( electric refrigerators, rinsing machines, carcase of dead animate beings, old Surs, vehicle parts ) oil, asbestos sheet and all kind of chemicals are non left out. ( Environmental Agency 2009 ) . This offense cost land proprietors an estimated 100 million annually and local governments an estimated 44million annually to clean up. ( Environmental Agency 2009 ) . It besides attracts a punishment a upper limit of two old ages imprisonment and or an limitless mulct ( Liver Pool City Council 2008 ) every bit good as & A ; lb ; 50,000 in Magistrate Court. ( Environmental Agency 2009 ) . There is a national fly tipping database funded by the authorities which is managed by the environmental bureau, it is known as fly – gaining control, entirely for the intents of undertaking fly- tipping. Graffitti: It is referred to as an act of hooliganism which is on the addition, it entails written, painted or scratched on other people ‘s belongings. Persons every bit good as packs leave a signature grade where they visit such as Bridgess, motor ways, public topographic points, and overseas telegram equipment boxes, unoccupied edifices are non left out. ( Solihull Metropolitan Borough Council 2009 ) . Upon strong belief under subdivision 1 of the Criminal Damage Act 1971 the punishment is 10 old ages imprisonment. This offense is so serious that it can be heard in either a Magistrate or Crown Court. ( Solihull Metropolitan Borough Council 2009 ) . A fixed punishment of & A ; lb ; 75, which will be reduced to & A ; lb ; 50 if received within seven yearss from the day of the month which the punishment was issued. ( Solihull Metropolitan Borough Council 2009 ) . Dog Fouling: This is the act of go forthing your Canis familiaris or the Canis familiaris under your attention to foul on tracts and unfastened infinites, with cleaning up after it. This Canis familiaris foul when in contact with the human oculus can do sightlessness ; people might step on it and transport the crud into their places. This offense attracts a fixed punishment notice of & A ; lb ; 50 which you must pay to the council within 14days, else you will be prosecuted. ( Gateshead Council 2008 ) . Persons can assist to look into environmental offense by study an environmental offense in their community to the local governments through their web sites.